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Structure of 149505-94-2
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Tert-butyl 4-hydroxybenzylcarbamate features a phenolic hydroxyl group flanked by a tert-butyl carbamate protecting group, enabling selective deprotection under mild acidic conditions. This combination imparts stability during synthetic manipulations while facilitating precise functionalization in peptide and small-molecule synthesis workflows.
Tert-butyl 4-hydroxybenzylcarbamate serves as a versatile protecting group for primary amines, enabling selective functionalization in complex molecule synthesis. The tert-butyl carbamate moiety offers excellent stability under basic and mildly acidic conditions, while the phenolic hydroxyl group permits orthogonal modifications. It facilitates efficient coupling reactions and is readily cleaved under mild acidic conditions, making it ideal for iterative synthetic sequences in medicinal chemistry and API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P260-P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501
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Lot numbers can be found on the outside label of a product: