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Structure of 150517-75-2
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This bench-stable arylamine features a fluorinated aromatic ring paired with a methoxy group, enabling enhanced metabolic stability and tunable electronic properties. The primary amine functionality facilitates straightforward conjugation and incorporation into bioactive molecules, making it valuable for medicinal chemistry applications.
(2-Fluoro-6-methoxyphenyl)methanamine serves as a valuable building block for bioactive heterocycles and pharmaceutical intermediates, enabling efficient access to substituted anilines via standard coupling reactions. Its ortho-fluoro and para-methoxy substituents provide enhanced electronic modulation and metabolic stability, while the benzylic amine functionality offers high reactivity in amide bond formation, Mannich reactions, and electrophilic aromatic substitution. Bench-stable and readily purified by distillation or chromatography, it functions effectively in multi-step syntheses of CNS-targeted compounds and kinase inhibitors.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: