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Structure of 151157-46-9
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This cyclobutane carboxylic acid features a para-fluorophenyl substituent, delivering enhanced electron-withdrawing character and improved metabolic stability. The rigid cyclobutane scaffold provides conformational control, while the carboxylic acid functionality enables direct derivatization or salt formation. Ideal for medicinal chemistry campaigns requiring lipophilic, bioactive scaffolds with defined stereochemistry.
1-(4-Fluorophenyl)cyclobutane-1-carboxylic acid serves as a valuable building block in medicinal chemistry, enabling the construction of bioactive scaffolds through standard functional group transformations. Its cyclobutane core provides conformational rigidity, while the pendant 4-fluorophenyl group enhances metabolic stability and modulates lipophilicity. The carboxylic acid functionality facilitates direct coupling reactions or derivatization, offering versatility in peptide and small-molecule synthesis. Bench-stable and compatible with common purification methods, it supports efficient route development for target-oriented synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: