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Structure of 151414-46-9
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3,5-Difluoro-2-nitrophenol features a highly electron-deficient aromatic core stabilized by dual fluorine substituents and a nitro group at the ortho position. This combination enhances reactivity in coupling processes while maintaining bench stability under standard conditions. The molecule integrates readily into advanced synthetic sequences requiring strong electrophilic character or precise electronic tuning.
3,5-Difluoro-2-nitrophenol serves as a valuable building block in medicinal chemistry and agrochemical synthesis, enabling the construction of fluorinated heterocyclic scaffolds via standard electrophilic substitution and coupling reactions. Its dual electron-withdrawing nitro and fluoro substituents enhance reactivity in nucleophilic aromatic substitution processes, while its bench-stable crystalline form facilitates handling and purification. Functions as a key intermediate in the development of bioactive molecules requiring targeted fluorination and nitrogen functionality.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: