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Structure of 152192-95-5
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tert-Butyl ethyl(2-hydroxyethyl)carbamate features a protected amine moiety flanked by sterically hindered tert-butyl and ethyl groups, offering enhanced stability under standard conditions. The pendant hydroxyethyl side chain enables facile derivatization or incorporation into multi-step synthetic sequences. This combination of robust protection and functional handle delivers reliable performance in peptide coupling and small molecule synthesis workflows.
tert-Butyl ethyl(2-hydroxyethyl)carbamate serves as a stable, bench-friendly carbamate protecting group for primary amines, enabling selective N-protection under mild conditions. It facilitates orthogonal functional group manipulation in complex molecule synthesis, offering ease of installation and reliable deprotection with trifluoroacetic acid. The molecule exhibits excellent compatibility with diverse reaction types, including amide coupling and metal-catalyzed transformations, making it a practical choice for iterative synthetic strategies in medicinal chemistry and API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: