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Structure of 1528607-78-4
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This brominated aryl ketone features a sterically accessible carbonyl group flanked by electron-withdrawing fluorine atoms, enabling efficient coupling in cross-coupling reactions. The para-bromo substituent serves as a reactive handle for palladium-catalyzed transformations, while the difluorophenyl core enhances metabolic stability and lipophilicity in medicinal chemistry applications.
1-(4-Bromo-3,5-difluorophenyl)ethanone serves as a versatile building block in medicinal chemistry and materials science, enabling efficient construction of complex aryl ketones. Its bromine and difluoro substituents provide orthogonal reactivity for palladium-catalyzed cross-coupling and enhanced metabolic stability in bioactive scaffolds. The compound exhibits excellent bench stability, facilitates straightforward purification via recrystallization, and functions reliably in standard coupling and functionalization protocols.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H332
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501
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Lot numbers can be found on the outside label of a product: