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Structure of 1545675-69-1
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1-Cyclobutyl-1H-pyrazole-4-carbaldehyde features a pyrazole core bearing a cyclobutyl substituent and an aldehyde handle at the 4-position. This electron-deficient aldehyde integrates readily into diversification workflows, offering a rigid, sterically constrained scaffold for medicinal chemistry and materials synthesis under standard conditions.
1-Cyclobutyl-1H-pyrazole-4-carbaldehyde serves as a versatile building block for heterocyclic synthesis, enabling efficient access to bioactive scaffolds. Its aldehyde functionality facilitates nucleophilic additions, reductive aminations, and Ugi-type reactions with high functional group tolerance. The cyclobutyl substituent enhances metabolic stability and modulates lipophilicity, making it valuable in medicinal chemistry lead optimization. Bench-stable and readily purified by flash chromatography, it functions reliably in standard synthetic workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P501
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Lot numbers can be found on the outside label of a product: