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tert-Butyl ((1R,2R)-2-hydroxycyclohexyl)carbamate

  • CAS No. 155975-19-2

  • Cat. No. CS-0058568
  • Purity≥95%
  • MDL No.MFCD11656036
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

tert-Butyl ((1R,2R)-2-hydroxycyclohexyl)carbamate|CS-0058568

Structure of 155975-19-2

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Description

tert-Butyl ((1R,2R)-2-hydroxycyclohexyl)carbamate is a chiral auxiliary featuring a rigid cyclohexane scaffold with a stereodefined hydroxyl group and a bench-stable carbamate protecting group. This configuration enables selective functionalization in asymmetric synthesis, particularly in the installation of stereocenters via dihydroxylation or oxidation protocols. The protected alcohol remains inert under many reaction conditions while allowing controlled deprotection post-functionalization.

Application

tert-Butyl ((1R,2R)-2-hydroxycyclohexyl)carbamate serves as a stereochemically defined chiral building block for cyclohexane-based scaffolds. The protected amine and secondary alcohol functionalities enable orthogonal derivatization in synthetic sequences. Its bench-stable nature and compatibility with standard coupling and reduction protocols facilitate efficient access to complex cyclic architectures. Functions effectively in asymmetric synthesis and medicinal chemistry campaigns requiring rigid, stereoregular frameworks.

General Information

  • CAS No. 155975-19-2
  • Cat. No. CS-0058568
  • Purity ≥95%
  • MDL No. MFCD11656036
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₂₁NO₃
  • Molecular Weight 215.29
  • Synonym(s) (1R,2R)-trans-N-Boc-2-aminocyclohexanol
  • SMILES O[C@H]1[C@H](NC(OC(C)(C)C)=O)CCCC1

Computational Chemistry Data

  • TPSA   58.56
  • LogP   1.8146
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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