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CS-W001157 4
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1,4,5,6-Tetrahydropyrrolo[3,4-c]pyrazole dihydrochloride

  • CAS No. 157327-47-4

  • Cat. No. CS-0018950
  • Purity≥95%
  • MDL No.MFCD08457551

*For research and further manufacturing use only, not for direct human use.

1,4,5,6-Tetrahydropyrrolo[3,4-c]pyrazole dihydrochloride|CS-0018950

Structure of 157327-47-4

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General Information

  • CAS No. 157327-47-4
  • Cat. No. CS-0018950
  • Purity ≥95%
  • MDL No. MFCD08457551
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₉Cl₂N₃
  • Molecular Weight 182.05
  • Synonym(s) 1,4,5,6-Tetrahydropyrrolo[3,4-c]pyrazoledihydrochloride
  • SMILES [H]Cl.[H]Cl.C1(CNC2)=C2C=NN1

Description

This tetrahydropyrrolopyrazole dihydrochloride features a rigid, electron-rich heterocyclic core that integrates seamlessly into bioactive scaffolds. The dihydrochloride salt enhances solubility and stability under standard conditions, enabling efficient incorporation into medicinal chemistry campaigns without requiring specialized handling.

Application

1,4,5,6-Tetrahydropyrrolo[3,4-c]pyrazole dihydrochloride serves as a versatile heterocyclic building block for medicinal chemistry and process development. Its stable dihydrochloride form enhances solubility and handling, while the fused ring system enables efficient incorporation into bioactive scaffolds. The core structure facilitates C–H functionalization and transition-metal-catalyzed coupling reactions, offering robust access to complex nitrogen-containing architectures relevant to drug discovery.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   40.71
  • LogP   0.8565
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   0

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