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Structure of 157924-46-4
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5-Iodopyrimidine-2,4-diamine serves as a key scaffold for constructing functionalized pyrimidine derivatives. The iodine substituent enables efficient cross-coupling reactions, while the diamine functionality provides dual sites for conjugation. This compound integrates readily into bioactive molecule synthesis under standard conditions.
5-Iodopyrimidine-2,4-diamine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions for the construction of biologically relevant pyrimidine scaffolds. The iodide group facilitates efficient Suzuki, Stille, and Negishi couplings, while the diamino functionality provides sites for derivatization or metal coordination. Its bench-stable nature and compatibility with diverse reaction conditions make it suitable for iterative synthesis and library generation.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: