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Structure of 159873-64-0
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1-(6-Nitrobenzo[d][1,3]dioxol-5-yl)ethanol features a nitro-substituted benzodioxole core paired with a primary alcohol functionality, enabling direct conjugation or derivatization. The electron-deficient aromatic ring enhances reactivity in nucleophilic substitution processes, while the pendant hydroxyl group offers polarity and solubility advantages. This scaffold serves as a key building block for bioactive molecule synthesis.
1-(6-Nitrobenzo[d][1,3]dioxol-5-yl)ethanol serves as a versatile synthetic intermediate for nitro-substituted benzodioxole scaffolds. Its benzylic alcohol functionality enables straightforward derivatization via oxidation, protection, or coupling reactions. The molecule exhibits good bench stability and facilitates access to bioactive heterocycles commonly found in medicinal chemistry campaigns, particularly those requiring electron-withdrawing nitro groups adjacent to oxygen-rich frameworks.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: