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Structure of 160938-18-1
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4-Chloro-2-iodo-1-nitrobenzene features a strategically positioned nitro group flanked by chlorine and iodine substituents, enabling direct coupling in cross-coupling reactions. This electron-deficient aromatic scaffold supports efficient palladium-catalyzed transformations under mild conditions. The ortho-iodo functionality facilitates rapid functionalization while maintaining stability during storage and handling.
4-Chloro-2-iodo-1-nitrobenzene serves as a versatile building block in cross-coupling chemistry, enabling the construction of biaryl scaffolds via Pd-catalyzed reactions. The ortho-iodo and para-chloro groups provide orthogonal reactivity for sequential functionalization, while the nitro group offers a handle for reduction and downstream heterocycle formation. Bench-stable and compatible with standard synthetic workflows, it facilitates efficient access to complex substituted aromatics used in medicinal chemistry and materials science.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: