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Structure of 32337-97-6
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1-Chloro-2-iodo-3-nitrobenzene features a tri-substituted benzene core with orthogonal reactivity profiles. The electron-deficient aromatic ring enables palladium-catalyzed cross-coupling, while the iodine moiety serves as a high-efficiency coupling handle. This compound integrates seamlessly into complex molecular architectures under mild conditions.
1-Chloro-2-iodo-3-nitrobenzene serves as a versatile dihalogenated building block for palladium-catalyzed cross-coupling reactions, enabling sequential functionalization at distinct aromatic positions. The chloro group facilitates Suzuki-Miyaura coupling, while the iodo moiety supports efficient Stille or Negishi transformations under mild conditions. Its nitro functionality provides a handle for selective reduction and downstream heterocycle formation. The compound exhibits good bench stability and is compatible with standard purification protocols, making it well-suited for iterative synthesis in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: