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Structure of 1612172-62-9
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This pyrazole boronate integrates a cyclopropanesulfonyl group and a tetramethyl-1,3,2-dioxaborolane moiety, enabling efficient cross-coupling under mild conditions. The sterically shielded boronate resists protodeboronation, while the sulfonyl substituent enhances solubility and metabolic stability in biopharmaceutical applications.
1-(Cyclopropanesulfonyl)-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole serves as a versatile boron-containing building block for Suzuki-Miyaura cross-coupling reactions. The tetramethylborolane group enables efficient coupling with aryl and heteroaryl halides under mild conditions, while the cyclopropanesulfonyl moiety provides enhanced stability and orthogonal reactivity. This compound facilitates the construction of complex pyrazole-based scaffolds commonly found in medicinal chemistry and agrochemical research, offering excellent bench stability and straightforward purification.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H332
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P501
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Lot numbers can be found on the outside label of a product: