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2-Methyl-2,6-diazaspiro[3.3]heptane dihydrochloride

  • CAS No. 1630082-57-3

  • Cat. No. CS-0151113
  • Molecule weight185.09
  • Purity≥95%
  • MDL No.MFCD26954754

*For research and further manufacturing use only, not for direct human use.

2-Methyl-2,6-diazaspiro[3.3]heptane dihydrochloride|CS-0151113

Structure of 1630082-57-3

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General Information

  • CAS No. 1630082-57-3
  • Cat. No. CS-0151113
  • Purity ≥95%
  • MDL No. MFCD26954754
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₄Cl₂N₂
  • Molecular Weight 185.09
  • Synonym(s) 2-Methyl-2,6-diaza-spiro[3.3]heptane dihydrochloride
  • SMILES CN1CC2(CNC2)C1.Cl.Cl

Description

2-Methyl-2,6-diazaspiro[3.3]heptane dihydrochloride delivers a rigid, bicyclic scaffold with dual nitrogen atoms positioned for strategic functionalization. This spirocyclic core exhibits enhanced solubility and stability under standard conditions, enabling efficient incorporation into bioactive molecules. The dihydrochloride salt form improves handling and crystallinity, facilitating use in medicinal chemistry and process development workflows.

Application

2-Methyl-2,6-diazaspiro[3.3]heptane dihydrochloride serves as a rigid, bicyclic diamine scaffold enabling precise spatial positioning of nitrogen functionalities. Its stability under standard synthetic conditions and compatibility with diverse coupling reactions facilitate efficient access to spirocyclic heterocycles. The dihydrochloride salt enhances solubility and simplifies handling, making it well-suited for medicinal chemistry applications requiring controlled basicity and defined stereochemistry.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   15.27
  • LogP   0.365
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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