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CS-W001157 4
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tert-Butyl N-({3-aminobicyclo[1.1.1]pentan-1-yl}methyl)carbamate

  • CAS No. 1630906-49-8

  • Cat. No. CS-0048094
  • Purity≥95%
  • MDL No.MFCD27987306
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

tert-Butyl N-({3-aminobicyclo[1.1.1]pentan-1-yl}methyl)carbamate|CS-0048094

Structure of 1630906-49-8

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Description

tert-Butyl N-({3-aminobicyclo[1.1.1]pentan-1-yl}methyl)carbamate features a rigid bicyclo[1.1.1]pentane scaffold that imparts exceptional metabolic stability and conformational restraint. The pendant amine enables straightforward derivatization, while the tert-butyl carbamate group provides robust protection under standard conditions. This combination delivers a versatile, bench-stable building block for medicinal chemistry campaigns requiring enhanced physicochemical properties.

Application

tert-Butyl N-({3-aminobicyclo[1.1.1]pentan-1-yl}methyl)carbamate serves as a stable, bench-ready amine protecting group derivative featuring a rigid bicyclic core. Its tertiary amine functionality enables efficient incorporation into diverse synthetic sequences, particularly in the construction of constrained peptidomimetics and bioactive heterocycles. The carbamate moiety offers orthogonal deprotection compatibility and facilitates purification via standard chromatographic methods.

General Information

  • CAS No. 1630906-49-8
  • Cat. No. CS-0048094
  • Purity ≥95%
  • MDL No. MFCD27987306
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₂₀N₂O₂
  • Molecular Weight 212.29
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)NCC12CC(N)(C1)C2

Computational Chemistry Data

  • TPSA   64.35
  • LogP   1.3925
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 3259
Class : 8
Packing Group :
Hazard Statements : H315-H318-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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