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Structure of 16357-83-8
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4-Aminopyrimidine-5-carbaldehyde features a conjugated pyrimidine core with complementary amine and aldehyde functionalities, enabling direct integration into heterocyclic scaffolds. This bifunctional molecule supports efficient coupling reactions and serves as a key intermediate in the synthesis of kinase inhibitors and bioactive nitrogen-rich architectures.
4-Aminopyrimidine-5-carbaldehyde serves as a versatile building block in medicinal chemistry, enabling the synthesis of pyrimidine-based heterocycles through standard condensation and coupling reactions. Its dual functionality—primary amine and aldehyde—facilitates orthogonal derivatization, supporting diverse scaffold elaboration. The compound exhibits good bench stability and is compatible with common protecting group strategies, making it well-suited for iterative synthesis workflows in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H317
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Precautionary Statements : P261-P264-P270-P272-P280-P302+P352-P330-P362+P364-P501
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Lot numbers can be found on the outside label of a product: