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Structure of 1637208-14-0
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(3-Cyano-4-hydroxyphenyl)boronic acid features a boronic acid group ortho to a phenolic hydroxyl and para to a nitrile, enabling selective conjugation in Suzuki-Miyaura coupling reactions. The electron-withdrawing cyano moiety enhances boronate stability and modulates reactivity, while the hydroxyl group supports hydrogen bonding and solubility in polar media. This combination delivers reliable performance under standard conditions for constructing complex aryl architectures.
(3-Cyano-4-hydroxyphenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura coupling reactions, enabling efficient access to biaryl scaffolds with retained functional group integrity. The cyano and hydroxyl groups provide orthogonal reactivity and enhanced solubility, while the boronic acid moiety offers excellent bench stability and compatibility with diverse reaction conditions. This compound facilitates the construction of complex heterocyclic and pharmaceutical intermediates under standard catalytic protocols.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: