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Structure of 66909-29-3
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6-Chloro-5-methylnicotinic acid features a chlorine atom at the 6-position and a methyl group at the 5-position of the nicotinic acid scaffold, delivering enhanced electron-withdrawing character and steric influence. This configuration supports direct incorporation into heterocyclic systems and facilitates downstream functionalization in medicinal chemistry campaigns.
6-Chloro-5-methylnicotinic acid serves as a versatile building block in medicinal chemistry, enabling direct incorporation into bioactive heterocycles via standard coupling and cyclization protocols. Its orthogonal functional groups—chloro at C6 and methyl at C5—facilitate selective derivatization, while the carboxylic acid supports facile amide formation or esterification. Bench-stable and compatible with common reaction conditions, it functions effectively in the synthesis of pharmaceutical intermediates and agrochemical scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: