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Structure of 16378-06-6
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This thiophene-containing carboxylic acid integrates a conjugated heterocyclic scaffold with a flexible aliphatic chain, enabling efficient incorporation into bioactive molecules. The para-positioned thiophene ring enhances π-stacking and electronic modulation, while the terminal carboxyl group facilitates derivatization via amide coupling or esterification under standard conditions.
3-(Thiophen-3-yl)propanoic acid serves as a versatile building block for synthesizing bioactive heterocycles and pharmaceutical intermediates. Its conjugated thiophene–alkyl carboxylic acid motif enables reliable coupling reactions, including amide formation and esterification, with excellent functional group tolerance. The compound exhibits good bench stability and is readily purified by recrystallization, facilitating its use in scalable synthetic routes.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: