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Structure of 1638761-19-9
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6-Methoxy-2-azaspiro[3.3]heptane hydrochloride is a bench-stable, moisture-tolerant heterocyclic scaffold featuring a spirocyclic architecture with a tertiary amine and a methoxy substituent. This configuration enhances solubility and metabolic stability, enabling efficient incorporation into bioactive molecule design. The hydrochloride salt improves handling and crystallinity for synthetic workflows.
6-Methoxy-2-azaspiro[3.3]heptane hydrochloride serves as a rigid, conformationally constrained scaffold for medicinal chemistry applications. Its spirocyclic core provides enhanced metabolic stability and defined spatial orientation of substituents. The tertiary amine functionality enables salt formation for improved solubility and crystallinity, while the methoxy group offers moderate electron donation and compatibility with standard synthetic transformations. This compound facilitates the construction of complex heterocyclic architectures and functions as a versatile building block in lead optimization campaigns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: