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CS-W001157 4
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2-Oxa-8-azaspiro[4.5]decane hydrochloride

  • CAS No. 479195-19-2

  • Cat. No. CS-B0027
  • Molecule weight177.67
  • Purity≥97%
  • MDL No.MFCD11035930

*For research and further manufacturing use only, not for direct human use.

2-Oxa-8-azaspiro[4.5]decane hydrochloride|CS-B0027

Structure of 479195-19-2

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General Information

  • CAS No. 479195-19-2
  • Cat. No. CS-B0027
  • Purity ≥97%
  • MDL No. MFCD11035930
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₆ClNO
  • Molecular Weight 177.67
  • Synonym(s) 2-Oxa-8-azaspiro[4.5]decane, hydrochloride
  • SMILES Cl[H].N(CC1)CCC21COCC2

Description

This spirocyclic amine hydrochloride delivers a rigid, conformationally constrained scaffold ideal for medicinal chemistry. The fused 2-oxa-8-azaspiro[4.5]decane core combines oxygen and nitrogen heteroatoms within a strained bicyclic framework, enabling precise spatial orientation of functional groups. This structural rigidity enhances target binding affinity while improving metabolic stability. The salt form ensures excellent solubility and handling under standard bench conditions.

Application

2-Oxa-8-azaspiro[4.5]decane hydrochloride serves as a versatile spirocyclic scaffold in medicinal chemistry, enabling efficient access to constrained heterocyclic architectures. Its stability under standard reaction conditions and compatibility with diverse functional groups facilitate downstream derivatization in target-oriented synthesis. The hydrochloride salt enhances solubility and handling for bench-scale applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   21.26
  • LogP   1.1983
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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