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Structure of 1638767-26-6
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This bicyclic alcohol features a constrained three-membered ring system bearing a primary amine and hydroxyl group in close proximity. The scaffold imparts high rigidity and directional polarity, enabling precise spatial control in molecular design. Ideal for integrating bioactive motifs into peptidomimetics, fragment-based libraries, and macrocyclic architectures where conformational restriction enhances target affinity.
{3-Aminobicyclo[1.1.1]pentan-1-yl}methanol serves as a rigid, sterically constrained scaffold for medicinal chemistry applications, enabling the exploration of conformationally restricted analogs. The primary amine and hydroxyl groups provide orthogonal functional handles for derivatization, while the bicyclic core offers excellent bench stability and compatibility with standard coupling protocols. Its defined three-dimensional geometry facilitates predictable spatial orientation in ligand-receptor interactions, making it a valuable building block for targeted compound libraries.
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3259
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H314
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501
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Lot numbers can be found on the outside label of a product: