Methyl 4-chloro-3-hydroxybenzoate

Name: Methyl 4-chloro-3-hydroxybenzoate
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 166272-81-7
Cat. No. CS-W003784
Purity≥98%
MDL No.MFCD11505968

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Methyl 4-chloro-3-hydroxybenzoate|CS-W003784

Structure of 166272-81-7

Size

Price

Quantity

* Please select Quantity before adding items.

Description

Methyl 4-chloro-3-hydroxybenzoate features a strategically positioned hydroxyl group flanking a chlorinated aromatic ring, enabling selective derivatization in synthetic sequences. This electron-deficient ester integrates readily into complex molecular architectures under standard conditions.

Application

Methyl 4-chloro-3-hydroxybenzoate serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling direct functionalization at the phenolic hydroxyl group. The ortho-chloro and ester functionalities provide orthogonal reactivity for palladium-catalyzed coupling, electrophilic substitution, or selective derivatization. Bench-stable and readily purified by recrystallization, it facilitates efficient access to substituted benzene scaffolds relevant to pharmaceutical intermediates.

General Information

CAS No. 166272-81-7
Cat. No. CS-W003784
Purity ≥98%
MDL No. MFCD11505968
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₇ClO₃
Molecular Weight 186.59
Synonym(s) Benzoic acid, 4-chloro-3-hydroxy-, methyl ester
SMILES COC(C1=CC(O)=C(Cl)C=C1)=O

Computational Chemistry Data

TPSA 46.53
LogP 1.8322
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Chloride

Building Blocks Functional Group Ester

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

Methyl 4-chloro-3-hydroxybenzoate sigmaMethyl 4-chloro-3-hydroxybenzoate manufacturerMethyl 4-chloro-3-hydroxybenzoate priceMethyl 4-chloro-3-hydroxybenzoate structureMethyl 4-chloro-3-hydroxybenzoate SDSbuy Methyl 4-chloro-3-hydroxybenzoateMethyl 4-chloro-3-hydroxybenzoate supplierMethyl 4-chloro-3-hydroxybenzoate usesMethyl 4-chloro-3-hydroxybenzoate molecular weightprice of Methyl 4-chloro-3-hydroxybenzoateMethyl 4-chloro-3-hydroxybenzoate chemical name formula of Methyl 4-chloro-3-hydroxybenzoate

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

Methyl 4-chloro-3-hydroxybenzoate

CAS No. 166272-81-7

Recommended Products