Methyl 5-hydroxy-6-methoxynicotinate

Name: Methyl 5-hydroxy-6-methoxynicotinate
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 166742-16-1
Cat. No. CS-0150567
Molecule weight183.16
Purity≥97%
MDL No.MFCD16621825

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Methyl 5-hydroxy-6-methoxynicotinate|CS-0150567

Structure of 166742-16-1

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 166742-16-1
Cat. No. CS-0150567
Purity ≥97%
MDL No. MFCD16621825
Storage 4°C, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₉NO₄
Molecular Weight 183.16
Synonym(s) 3-Pyridinecarboxylic acid, 5-hydroxy-6-methoxy-, methyl ester
SMILES COC1=C(C=C(C=N1)C(=O)OC)O

Description

Methyl 5-hydroxy-6-methoxynicotinate is a bench-stable, moisture-tolerant heterocyclic ester featuring a hydroxyl group at the 5-position and a methoxy substituent at the 6-position. This electron-rich scaffold integrates readily into synthetic sequences requiring precise regiocontrol, enabling efficient access to functionalized pyridine derivatives under standard conditions.

Application

Methyl 5-hydroxy-6-methoxynicotinate serves as a versatile building block in synthetic organic chemistry, enabling access to functionalized pyridine derivatives through standard coupling and oxidation protocols. Its hydroxyl and methoxy groups offer orthogonal reactivity for selective derivatization, while the ester functionality supports transformations such as reduction, amidation, or cross-coupling. The compound exhibits good bench stability and facilitates purification via standard chromatographic methods, making it well-suited for medicinal chemistry and process development workflows.

Synthesis

Route1
- 13755-29-8
- In-stock
  
  59237-50-2
- ~%
- 166742-24-1
- In-stock
  
  166742-16-1
References
- RHONE-POULENC RORER LIMITED Patent: EP741707 B1, 1998 ;

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 68.65
LogP 0.5824
H_Acceptors 5
H_Donors 1
Rotatable_Bonds 2

Other Classifications

Building Blocks Functional Group Ester

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

Methyl 5-hydroxy-6-methoxynicotinate sigmaMethyl 5-hydroxy-6-methoxynicotinate manufacturerMethyl 5-hydroxy-6-methoxynicotinate priceMethyl 5-hydroxy-6-methoxynicotinate structureMethyl 5-hydroxy-6-methoxynicotinate SDSbuy Methyl 5-hydroxy-6-methoxynicotinateMethyl 5-hydroxy-6-methoxynicotinate supplierMethyl 5-hydroxy-6-methoxynicotinate usesMethyl 5-hydroxy-6-methoxynicotinate molecular weightprice of Methyl 5-hydroxy-6-methoxynicotinateMethyl 5-hydroxy-6-methoxynicotinate chemical name formula of Methyl 5-hydroxy-6-methoxynicotinate

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

Methyl 5-hydroxy-6-methoxynicotinate

CAS No. 166742-16-1

Recommended Products