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Structure of 16800-68-3
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1-Acetylindolin-3-one is a bench-stable heterocyclic ketone featuring a fused indoline core with a strategically positioned acetyl group. This configuration enables direct participation in Pd-catalyzed cross-coupling reactions and facilitates downstream functionalization in synthetic medicinal chemistry. The compound serves as a key intermediate for bioactive molecule scaffolds, particularly in kinase inhibitor development.
1-Acetylindolin-3-one serves as a versatile building block in synthetic organic chemistry, enabling efficient access to indole-based heterocycles and pharmaceutical scaffolds. Its acetyl group at the 1-position provides a stable, bench-ready ketone functionality with high tolerance for diverse reaction conditions. The molecule facilitates C–H functionalization, cyclization cascades, and transition-metal-catalyzed transformations, making it valuable for medicinal chemistry campaigns targeting kinase inhibitors and CNS agents.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: