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Structure of 264916-06-5
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tert-Butyl 5-aminoisoindoline-2-carboxylate features a sterically hindered tert-butyl ester group that enhances stability and simplifies purification. The amino-substituted isoindoline core provides a rigid, electron-rich scaffold ideal for coupling reactions in medicinal chemistry. This bench-stable intermediate integrates readily into complex molecular architectures via standard amine functionalization protocols.
tert-Butyl 5-aminoisoindoline-2-carboxylate serves as a versatile building block for isoindoline-based scaffolds in medicinal chemistry and materials science. The protected amine and carboxylate functionalities enable sequential transformations, including palladium-catalyzed couplings, reductive amination, and cyclization reactions. Its bench-stable nature and ease of purification support scalable synthesis of complex heterocycles and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: