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Structure of 170098-88-1
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1-Chloro-4-fluoro-2-methyl-5-nitrobenzene is a highly functionalized aryl halide featuring orthogonal reactivity at chlorine and fluorine sites. The electron-deficient aromatic ring, enhanced by the para-nitro group, enables efficient palladium-catalyzed cross-coupling. This bench-stable compound integrates readily into complex molecular architectures requiring precise substitution patterns.
1-Chloro-4-fluoro-2-methyl-5-nitrobenzene serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling palladium-catalyzed cross-coupling reactions due to its complementary halogen reactivity. The chloro group facilitates nucleophilic substitution under mild conditions, while the fluorine and nitro groups enhance electrophilicity and direct regioselective functionalization. Its bench-stable nature and compatibility with diverse reaction conditions make it well-suited for constructing complex aromatic scaffolds in process-scale applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: