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Structure of 170228-81-6
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This spirocyclic amino acid derivative features a protected tertiary amine and a carboxylic acid handle, enabling direct incorporation into peptide chains. The tert-butyl carbamate group ensures stability during synthesis, while the rigid spiro framework imparts conformational control. Ideal for constructing constrained peptidomimetics with enhanced metabolic resistance.
3-(tert-Butoxycarbonyl)-3-azaspiro[5.5]undecane-9-carboxylic acid serves as a versatile spirocyclic scaffold for medicinal chemistry campaigns, enabling efficient access to constrained heterocyclic architectures. The protected amine and carboxylic acid functionalities offer orthogonal reactivity, facilitating peptide coupling, selective deprotection, and downstream derivatization. Bench-stable and readily purified by standard chromatographic methods, it functions as a key building block in the synthesis of complex nitrogen-containing frameworks relevant to drug discovery.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: