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Structure of 873924-08-4
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tert-Butyl 9-oxo-3-azaspiro[5.5]undecane-3-carboxylate features a rigid spirocyclic scaffold with a ketone at C9 and a protected amine at N3, enabling direct functionalization at the 3-position. This configuration supports efficient access to complex nitrogen-containing polycycles in medicinal chemistry and natural product synthesis.
tert-Butyl 9-oxo-3-azaspiro[5.5]undecane-3-carboxylate serves as a versatile spirocyclic building block for the synthesis of complex nitrogen-containing scaffolds. The ketone at C9 enables selective reductions, enolate formations, and nucleophilic additions, while the protected amine at N3 provides orthogonal reactivity. Its tert-butyl ester facilitates mild deprotection under acidic conditions, and the rigid spirocyclic framework imparts conformational control, making it valuable in medicinal chemistry and target-oriented synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: