Vipivotide tetraxetan Ligand-Linker Conjugate

Name: Vipivotide tetraxetan Ligand-Linker Conjugate
Brand: ChemScene
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CAS No. 1703768-74-4
Cat. No. CS-0095890
Purity≥96%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
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Vipivotide tetraxetan Ligand-Linker Conjugate|CS-0095890

Structure of 1703768-74-4

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Description

Vipivotide tetraxetan ligand-linker conjugate enables site-specific radiolabeling via transchelation with metal isotopes. This stable, bifunctional construct combines a high-affinity targeting moiety with a robust tetraxetan chelator, facilitating efficient conjugation under physiological conditions. The linker ensures optimal spacing and bioavailability for diagnostic imaging applications.

Application

Vipivotide tetraxetan Ligand-Linker Conjugate serves as a robust bifunctional chelator for radiolabeling applications, enabling site-specific conjugation of metal isotopes such as ⁶⁸Ga and ¹⁷⁷Lu to targeting peptides. Its tetraazacyclododecane-tetraacetic acid (DOTA) core provides high stability and affinity for radiometals, while the linker facilitates efficient coupling under physiological conditions. The conjugate exhibits excellent in vivo stability, minimal non-specific binding, and predictable pharmacokinetics, making it well-suited for precision imaging and targeted radionuclide therapy workflows in preclinical and clinical settings.

General Information

CAS No. 1703768-74-4
Cat. No. CS-0095890
Purity ≥96%
MDL No. None
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₃₃H₄₅N₅O₉
Molecular Weight 655.74
Synonym(s) PSMA-617 Ligand-Linker Conjugate
SMILES O=C(O)[C@H](CCCCNC([C@H](CC1=CC=C2C=CC=CC2=C1)NC([C@H]3CC[C@H](CN)CC3)=O)=O)NC(N[C@H](C(O)=O)CCC(O)=O)=O

Computational Chemistry Data

TPSA 237.25
LogP 1.9891
H_Acceptors 7
H_Donors 8
Rotatable_Bonds 18

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Other Classifications

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Life Science Linker Non-PEG linker

Life Science Amino Acids and their Derivatives Lysine and derivatives

Life Science ADC Related Compound Non-cleavable linker

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Antibody-Drug Conjugates (ADC) Preparation Research Reagents Cross-Linkers

Chemical Biology Peptide Chemistry Unnatural Amino Acid Derivatives

Biochemistry Biochemicals and Reagents Antibody-Drug Conjugates (ADC) Preparation Research Reagents Cross-Linkers

Biochemistry Pharmaceutical Development and Drug Discovery Research Antibody-Drug Conjugates (ADC) Preparation Research Reagents Cross-Linkers

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Vipivotide tetraxetan Ligand-Linker Conjugate

CAS No. 1703768-74-4

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