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CS-W001157 4
Total: USD 88.00

7-Amino-4-(trifluoromethyl)coumarin

  • CAS No. 53518-15-3

  • Cat. No. CS-7725
  • Molecule weightNone
  • Purity≥97%
  • MDL No.MFCD00006858

*For research and further manufacturing use only, not for direct human use.

7-Amino-4-(trifluoromethyl)coumarin|CS-7725

Structure of 53518-15-3

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General Information

  • CAS No. 53518-15-3
  • Cat. No. CS-7725
  • Purity ≥97%
  • MDL No. MFCD00006858
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₆F₃NO₂
  • Molecular Weight None
  • Synonym(s) Coumarin 151; AFC
  • SMILES O=C1C=C(C(F)(F)F)C2=C(O1)C=C(N)C=C2

Description

7-Amino-4-(trifluoromethyl)coumarin (AFC) is a novel fluorescent marker used for the detection of proteinases.Suitable as laser dye

Synthesis

  • Route1
    • null|null
      63450-46-4
    • ~46%
    • In-stock
      7-Amino-4-(trifluoromethyl)coumarin|CS-7725
      53518-15-3

    References

    • Kathuria, Abha; Priya, Nivedita; Chand, Karam; Singh, Prabhjot; Gupta, Anjali; Jalal, Sarah; Gupta, Shilpi; Raj, Hanumantharao G.; Sharma, Sunil K. Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 4 p. 1624 - 1638
  • Route2
    • null|null
      372-31-6
    • null|null
      591-27-5
    • ~98%
    • In-stock
      7-Amino-4-(trifluoromethyl)coumarin|CS-7725
      53518-15-3

    References

    • Wang, Hongshe Monatshefte fur Chemie, 2013 , vol. 144, # 3 p. 411 - 414
  • Route3
    • null|null
      372-31-6
    • null|null
      591-27-5
    • ~83%
    • 7-Hydroxy-4-(trifluoromethyl)quinolin-2(1H)-one|CS-1057414
      73496-29-4
    • In-stock
      7-Amino-4-(trifluoromethyl)coumarin|CS-7725
      53518-15-3

    References

    • Tetrahedron Letters, , vol. 43, # 50 p. 9195 - 9197

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   56.23
  • LogP   2.394
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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