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CS-W001157 4
Total: USD 88.00

6-(((tert-Butoxycarbonyl)amino)methyl)picolinic acid

  • CAS No. 171670-07-8

  • Cat. No. CS-0094520
  • Purity≥95%
  • MDL No.MFCD06657528
  • HazMat Fee +

    HazMat Fee

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

6-(((tert-Butoxycarbonyl)amino)methyl)picolinic acid|CS-0094520

Structure of 171670-07-8

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Description

This Boc-protected picolinic acid derivative features a strategically positioned amine handle for facile conjugation, enabling direct incorporation into peptide and small-molecule scaffolds. The tert-butoxycarbonyl group provides robust protection under standard reaction conditions, while the pyridine ring offers enhanced solubility and stability in polar solvents.

Application

6-(((tert-Butoxycarbonyl)amino)methyl)picolinic acid serves as a versatile building block for the synthesis of bioactive heterocycles and peptide conjugates. The tert-butyl carbamate group provides excellent stability under basic conditions and facilitates selective deprotection during late-stage functionalization. Its pendant picolinic acid moiety enables direct coupling reactions, while the benzylic amine functionality supports orthogonal derivatization in multi-step syntheses. Functions reliably in standard SPPS and solution-phase workflows.

General Information

  • CAS No. 171670-07-8
  • Cat. No. CS-0094520
  • Purity ≥95%
  • MDL No. MFCD06657528
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₆N₂O₄
  • Molecular Weight 252.27
  • Synonym(s) 6-[(Boc-amino)methyl]-2-pyridinecarboxylic acid
  • SMILES O=C(C1=NC(CNC(OC(C)(C)C)=O)=CC=C1)O

Computational Chemistry Data

  • TPSA   88.52
  • LogP   1.8045
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   3

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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