Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

(6-Bromo-3H-imidazo[4,5-b]pyridin-2-yl)methanol

  • CAS No. 172648-19-0

  • Cat. No. CS-0084860
  • Purity≥95%
  • MDL No.MFCD09750272

*For research and further manufacturing use only, not for direct human use.

(6-Bromo-3H-imidazo[4,5-b]pyridin-2-yl)methanol|CS-0084860

Structure of 172648-19-0

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 172648-19-0
  • Cat. No. CS-0084860
  • Purity ≥95%
  • MDL No. MFCD09750272
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₆BrN₃O
  • Molecular Weight 228.05
  • Synonym(s) 3H-imidazo[4,5-b]pyridine-2-methanol, 6-bromo-
  • SMILES OCC1=NC2=CC(Br)=CN=C2N1

Description

This boronate-bearing imidazopyridine derivative features a reactive methanol handle for Suzuki-Miyaura coupling, enabling efficient integration into complex heterocycles. The bromo substituent provides orthogonal functionality for further diversification. Bench-stable and moisture-tolerant, it streamlines access to bioactive scaffolds in medicinal chemistry.

Application

(6-Bromo-3H-imidazo[4,5-b]pyridin-2-yl)methanol serves as a versatile building block for constructing imidazopyridine-based scaffolds in medicinal chemistry. The bromo group enables palladium-catalyzed cross-coupling reactions, while the pendant primary alcohol facilitates derivatization via esterification, etherification, or oxidation to aldehyde. Its bench-stable nature and compatibility with common protecting group strategies make it well-suited for multi-step synthesis of functionalized heterocycles.

Synthesis

  • Route1

    References

    • Oguchi; Wada; Honma; Tanaka; Kaneko; Sakakibara; Ohsumi; Serizawa; Fujiwara; Horikoshi; Fujita Journal of Medicinal Chemistry, 2000 , vol. 43, # 16 p. 3052 - 3066
  • Route2

    References

    • Oguchi; Wada; Honma; Tanaka; Kaneko; Sakakibara; Ohsumi; Serizawa; Fujiwara; Horikoshi; Fujita Journal of Medicinal Chemistry, 2000 , vol. 43, # 16 p. 3052 - 3066

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   61.8
  • LogP   1.2127
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 172648-19-0 sigma172648-19-0 manufacturer172648-19-0 price172648-19-0 structure172648-19-0 SDSbuy 172648-19-0172648-19-0 supplier172648-19-0 uses172648-19-0 molecular weightprice of 172648-19-0172648-19-0 chemical name formula of 172648-19-0
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label