6-Ethynylpyridin-2-amine

Name: 6-Ethynylpyridin-2-amine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 173314-98-2
Cat. No. CS-0309307
Purity≥97%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 173314-98-2

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Description

6-Ethynylpyridin-2-amine delivers a reactive alkyne handle ortho to a primary amine, enabling efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC) for bioconjugation and materials assembly. This bench-stable, moisture-tolerant building block integrates seamlessly into functional molecular architectures.

Application

6-Ethynylpyridin-2-amine serves as a versatile building block in synthetic organic chemistry, enabling efficient access to substituted heterocycles via copper-catalyzed coupling reactions. Its orthogonal functionality—combining a terminal alkyne and a primary amine—facilitates modular assembly of complex scaffolds, including triazoles and conjugated systems. The compound exhibits excellent bench stability and compatibility with standard purification protocols, making it ideal for medicinal chemistry campaigns and process development workflows.

General Information

CAS No. 173314-98-2
Cat. No. CS-0309307
Purity ≥97%
MDL No. None
Storage 4°C, protect from light, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₆N₂
Molecular Weight 118.14
Synonym(s) 6-Ethynyl-2-pyridinaMine
SMILES C#CC1=NC(=CC=C1)N

Computational Chemistry Data

TPSA 38.91
LogP 0.6451
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

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Other Classifications

Building Blocks Functional Group Alkyne

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Life Science Click Chemistry Reagents Alkyne

Chemical Biology Pharmaceutical Development and Drug Discovery Research Conjugation Chemistry/Click Chemistry Terminal Alkynes

Chemical Biology Conjugation Chemistry/Click Chemistry Terminal Alkynes

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6-Ethynylpyridin-2-amine

CAS No. 173314-98-2

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