2-Amino-4,6-dimethylpyridine

Name: 2-Amino-4,6-dimethylpyridine
Brand: ChemScene
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CAS No. 5407-87-4
Cat. No. CS-W001149
Purity≥96%
MDL No.MFCD00006322

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Structure of 5407-87-4

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Description

2-Amino-4,6-dimethylpyridine features a pyridine core substituted with amino and two methyl groups at the 2, 4, and 6 positions, delivering enhanced electron density and steric protection. This configuration enables efficient coordination in transition metal catalysis and facilitates selective functionalization in synthetic routes. The compound exhibits robust stability under standard conditions and integrates seamlessly into heterocyclic scaffold development for medicinal chemistry applications.

Application

2-Amino-4,6-dimethylpyridine serves as a versatile building block in medicinal chemistry and catalyst design, enabling efficient access to substituted pyridine scaffolds. Its ortho-amino functionality facilitates palladium-catalyzed cross-coupling reactions, while the methyl groups enhance metabolic stability and modulate electronic properties. The compound exhibits excellent bench stability and compatibility with diverse functional groups, simplifying purification and integration into multi-step syntheses.

General Information

CAS No. 5407-87-4
Cat. No. CS-W001149
Purity ≥96%
MDL No. MFCD00006322
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₁₀N₂
Molecular Weight 122.17
Synonym(s) 6-Amino-2,4-lutidine
SMILES Cc1cc(C)nc(c1)N

Computational Chemistry Data

TPSA 38.91
LogP 1.28064
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07,GHS09
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335-H401-H411
Precautionary Statements : P261-P264-P270-P271-P273-P280-P302+P352-P305+P351+P338-P362-P391-P403+P233-P405-P501

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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2-Amino-4,6-dimethylpyridine

CAS No. 5407-87-4

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