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CS-W001157 4
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Isoxazol-4-ylmethanamine hydrochloride

  • CAS No. 173850-71-0

  • Cat. No. CS-0074165
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Isoxazol-4-ylmethanamine hydrochloride|CS-0074165

Structure of 173850-71-0

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General Information

  • CAS No. 173850-71-0
  • Cat. No. CS-0074165
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₇ClN₂O
  • Molecular Weight 134.56
  • Synonym(s) 1-isoxazol-4-ylmethanamine hydrochloride
  • SMILES NCC1=CON=C1.Cl

Description

Isoxazol-4-ylmethanamine hydrochloride delivers a stable, moisture-tolerant heterocyclic amine scaffold with enhanced solubility in aqueous and protic solvents. This bench-stable derivative integrates readily into medicinal chemistry campaigns targeting CNS-active compounds and bioconjugation workflows. The para-substituted isoxazole ring enables efficient coupling reactions under mild conditions, facilitating rapid access to functionalized intermediates for drug discovery applications.

Application

Isoxazol-4-ylmethanamine hydrochloride serves as a versatile building block for the synthesis of bioactive heterocycles, particularly in medicinal chemistry and agrochemical research. The isoxazole ring provides structural rigidity and metabolic stability, while the primary amine functionality enables straightforward derivatization via amidation, alkylation, and reductive amination. Its bench-stable hydrochloride salt form ensures ease of handling, purity, and compatibility with standard synthetic protocols.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   52.05
  • LogP   0.5551
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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