5-Bromo-2-pyridinemethanamine

Name: 5-Bromo-2-pyridinemethanamine
Brand: ChemScene
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CAS No. 173999-23-0
Cat. No. CS-W003275
Purity≥97%
MDL No.MFCD06213858

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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5-Bromo-2-pyridinemethanamine|CS-W003275

Structure of 173999-23-0

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Description

5-Bromo-2-pyridinemethanamine features a brominated pyridine core paired with a primary amine handle, enabling direct functionalization in transition metal-catalyzed couplings. This bench-stable derivative integrates readily into bioactive scaffolds and pharmaceutical intermediates, where the electron-deficient pyridine ring enhances reactivity in nucleophilic substitution processes.

Application

5-Bromo-2-pyridinemethanamine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its bromine substituent. The primary amine functionality facilitates direct derivatization or incorporation into peptide-like scaffolds. Its stability under standard bench conditions and compatibility with common protecting groups make it suitable for multi-step synthesis of heterocyclic drug candidates.

General Information

CAS No. 173999-23-0
Cat. No. CS-W003275
Purity ≥97%
MDL No. MFCD06213858
Storage -20°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₇BrN₂
Molecular Weight 187.04
Synonym(s) (5-Bromopyridin-2-yl)methanamine
SMILES NCC1=NC=C(Br)C=C1

Computational Chemistry Data

TPSA 38.91
LogP 1.3028
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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5-Bromo-2-pyridinemethanamine

CAS No. 173999-23-0

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