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CS-W001157 4
Total: USD 88.00

Riluzole

  • CAS No. 1744-22-5

  • Cat. No. CS-2156
  • Molecule weight234.20
  • Purity≥98%
  • MDL No.MFCD00210213

*For research and further manufacturing use only, not for direct human use.

Riluzole|CS-2156

Structure of 1744-22-5

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General Information

  • CAS No. 1744-22-5
  • Cat. No. CS-2156
  • Purity ≥98%
  • MDL No. MFCD00210213
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₅F₃N₂OS
  • Molecular Weight 234.20
  • Synonym(s) PK 26124
  • SMILES NC1=NC2=CC=C(OC(F)(F)F)C=C2S1

Application

Riluzole (CAS 1744-22-5) serves as the definitive USP reference standard for validating analytical methods and quality control assays in pharmaceutical testing. It ensures accuracy in potency and purity evaluations. This compound is essential for compliance with USP monographs, particularly for Riluzole Tablets, where consistent performance and identity verification are critical.

Synthesis

  • Route1
    • In-stock
      4-(Trifluoromethoxy)aniline|CS-W017380
      461-82-5
    • null|null
      1147550-11-5
    • ~78%
    • In-stock
      Riluzole|CS-2156
      1744-22-5

    References

    • Anzini, Maurizio; Chelini, Alessia; Mancini, Alessandra; Cappelli, Andrea; Frosini, Maria; Ricci, Lorenzo; Valoti, Massimo; Magistretti, Jacopo; Castelli, Loretta; Giordani, Antonio; Makovec, Francesco; Vomero, Salvatore Journal of Medicinal Chemistry, 2010 , vol. 53, # 2 p. 734 - 744
  • Route2
    • In-stock
      4-(Trifluoromethoxy)aniline|CS-W017380
      461-82-5
    • null|null
      333-20-0
    • ~87%
    • In-stock
      Riluzole|CS-2156
      1744-22-5

    References

    • BRISTOL-MYERS SQUIBB COMPANY; UNIVERSITE DE MONTREAL; LAWRENCE, Michael, R.; MILLER, Michael, M.; SEIFFERT, Dietmar, Alfred; POSY, Shoshana, L.; WONG, Pancras, C.; BANVILLE, Jacques; RUEDIGER, Edward, H.; DEON, Daniel, H.; MARTEL, Alain; TREMBLAY, Francois; GUY, Julia; LAVALLEE, Jean-Francois; GAGNON, Marc Patent: WO2013/163244 A1, 2013 ; Location in patent: Paragraph 00205; 00206 ;
  • Route3

    References

    • Jordan, Alfonzo D.; Luo, Chi; Reitz, Allen B. Journal of Organic Chemistry, 2003 , vol. 68, # 22 p. 8693 - 8696

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅱ
Hazard Statements : H300
Precautionary Statements : P264-P270-P330-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   48.14
  • LogP   2.7771
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   1

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