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CS-W001157 4
Total: USD 88.00

5-Thiazolamine

  • CAS No. 17721-00-5

  • Cat. No. CS-0054157
  • Purity≥96%
  • MDL No.MFCD09834069

*For research and further manufacturing use only, not for direct human use.

5-Thiazolamine|CS-0054157

Structure of 17721-00-5

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General Information

  • CAS No. 17721-00-5
  • Cat. No. CS-0054157
  • Purity ≥96%
  • MDL No. MFCD09834069
  • Storage -20°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₄N₂S
  • Molecular Weight None
  • Synonym(s) Thiazol-5-amine
  • SMILES NC1=CN=CS1

Application

5-Thiazolamine serves as a versatile building block in medicinal chemistry, enabling direct incorporation of the thiazole scaffold into bioactive molecules. Its primary amine functionality facilitates straightforward derivatization via acylation, alkylation, and coupling reactions, while the heterocyclic core exhibits favorable stability under standard synthetic conditions. This compound functions effectively in the construction of kinase inhibitors and antimicrobial agents, offering predictable reactivity and compatibility with common protecting group strategies.

Synthesis

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    References

    • Bioorganic and Medicinal Chemistry Letters, , vol. 18, # 17 p. 4794 - 4797
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      5-Thiazolamine|CS-0054157
      17721-00-5

    References

    • Helvetica Chimica Acta, , vol. 31, p. 470
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      5-Thiazolamine|CS-0054157
      17721-00-5

    References

    • Canadian Journal of Chemistry, , vol. 64, p. 1102 - 1107

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   38.91
  • LogP   0.7253
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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