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Structure of 17879-23-1
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trans-4-(Aminomethyl)cyclohexanemethanol features a rigid cyclohexane scaffold with equatorial amine and hydroxyl groups, enabling precise stereochemical control in medicinal chemistry. This bench-stable, moisture-tolerant building block integrates readily into bioactive scaffolds, particularly for CNS-targeted therapeutics and kinase inhibitors.
trans-4-(Aminomethyl)cyclohexanemethanol serves as a versatile bifunctional building block in medicinal chemistry, enabling the construction of constrained bioactive scaffolds. Its stable trans-cyclohexane framework provides defined stereochemistry, while the pendant primary amine and hydroxymethyl groups offer orthogonal reactivity for conjugation, derivatization, or protection strategies. The compound exhibits excellent bench stability and compatibility with standard peptide coupling and reductive amination protocols, facilitating efficient synthesis of target molecules in drug discovery campaigns.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3259
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H314-H318
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Precautionary Statements : P260-P264-P280-P304+P340-P330-P363-P405-P501
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Lot numbers can be found on the outside label of a product: