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Structure of 180340-69-6
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6-Amino-5-bromonicotinic acid features a brominated pyridine core with complementary amino and carboxylic acid functionalities. This electron-deficient heterocycle integrates readily into medicinal chemistry scaffolds, enabling direct coupling for peptide conjugation or transition metal-catalyzed functionalization under standard conditions.
6-Amino-5-bromonicotinic acid serves as a versatile building block in medicinal chemistry, enabling direct incorporation into heterocyclic scaffolds via palladium-catalyzed cross-coupling or nucleophilic substitution. The ortho-halogen and amino groups provide complementary reactivity for sequential functionalization, while the carboxylic acid facilitates derivatization through amide or ester formation. Bench-stable and readily purified by recrystallization, it functions efficiently in multi-step syntheses of bioactive molecules requiring regiocontrolled substitution on the pyridine core.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: