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Structure of 180465-84-3
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tert-Butyl 1,2-dihydrospiro[indole-3,4'-piperidine]-1'-carboxylate features a spirocyclic indole-piperidine architecture with a bench-stable tert-butyl carbamate protecting group. This scaffold integrates a rigid, three-dimensional core ideal for accessing complex alkaloid-like structures in medicinal chemistry and natural product synthesis.
tert-Butyl 1,2-dihydrospiro[indole-3,4'-piperidine]-1'-carboxylate serves as a versatile spirocyclic scaffold for medicinal chemistry campaigns, enabling efficient access to indole-piperidine architectures. Its tert-butyl carbamate group offers excellent bench stability and facilitates straightforward deprotection under mild acidic conditions. The molecule exhibits robust functional group tolerance and functions effectively in standard coupling and cyclization protocols, supporting rapid diversification in lead optimization workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: