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Structure of 1805105-03-6
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Methyl 2-(4-bromo-2,5-difluorophenyl)acetate is a bench-stable, moisture-tolerant building block featuring a sterically hindered aryl bromide and dual fluorine substituents. This electron-deficient phenyl moiety enables efficient coupling in palladium-catalyzed cross-coupling reactions. The ester functionality supports further derivatization under mild conditions.
Methyl 2-(4-bromo-2,5-difluorophenyl)acetate serves as a versatile building block in medicinal chemistry and cross-coupling synthesis. The bromo group enables palladium-catalyzed coupling reactions, while the difluorinated aryl moiety enhances metabolic stability and modulates electronic properties. The ester functionality allows for further derivatization, including reduction to the alcohol or hydrolysis to the carboxylic acid. Bench-stable and compatible with standard reaction conditions, it facilitates efficient access to complex fluorinated scaffolds relevant to pharmaceutical development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: