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Structure of 1821-36-9
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N-Cyclohexylaniline features a cyclohexyl group attached to the nitrogen of aniline, enhancing lipophilicity and steric bulk. This substitution improves solubility in organic media while maintaining nucleophilic reactivity at the aromatic ring. The compound serves as a stable, bench-friendly amine for coupling reactions, catalytic systems, and synthetic intermediates in pharmaceutical and materials chemistry.
N-Cyclohexylaniline serves as a stable, bench-friendly amine building block for constructing nitrogen-containing heterocycles and functionalized aromatic systems. Its cyclohexyl group enhances solubility and steric profile, enabling efficient coupling reactions with electrophiles such as acyl chlorides and sulfonyl chlorides. The molecule exhibits good functional group tolerance and facilitates straightforward purification, making it well-suited for medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: