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Structure of 18474-57-2
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4-Methyl-1H-indole-2-carboxylic acid features a sterically accessible carboxylic acid group at the 2-position of a methyl-substituted indole core, enabling direct conjugation in peptide and heterocyclic synthesis. This bench-stable derivative integrates readily into bioactive molecule scaffolds due to its electron-rich aromatic system and favorable solubility profile under standard conditions.
4-Methyl-1H-indole-2-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling efficient access to indole-based scaffolds through standard amide coupling and decarboxylation protocols. Its bench-stable nature and compatibility with diverse functional groups facilitate straightforward incorporation into target molecules. The methyl group at the 4-position provides a handle for further derivatization, while the carboxylic acid functionality supports direct conjugation or activation in peptide and macrocycle synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: