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Structure of 1850305-80-4
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tert-Butyl N-[3-(tetramethyl-1,3,2-dioxaborolan-2-yl)propyl]carbamate delivers a boronate handle tethered via a flexible alkyl chain to a robust tert-butyl carbamate protecting group. This combination enables efficient Suzuki-Miyaura coupling while maintaining stability under standard conditions. The molecule integrates seamlessly into diverse synthetic sequences requiring selective C–C bond formation and convenient deprotection.
tert-Butyl N-[3-(tetramethyl-1,3,2-dioxaborolan-2-yl)propyl]carbamate serves as a stable, bench-ready boron building block for Suzuki-Miyaura coupling reactions. The tetramethylboronate group enables efficient cross-coupling with aryl and vinyl halides under mild conditions, while the tert-butyl carbamate protects primary amines with orthogonal stability. This reagent facilitates rapid diversification of amine-containing scaffolds in medicinal chemistry and process synthesis, offering excellent functional group tolerance and straightforward purification.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P501
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Lot numbers can be found on the outside label of a product: