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Structure of 185147-08-4
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4-Fluoro-3-methylbenzonitrile features a strategically positioned nitrile group flanked by fluorine and methyl substituents, enabling precise tuning of electronic properties. This electron-deficient aromatic core integrates readily into pharmaceutical intermediates and agrochemical scaffolds, offering enhanced metabolic stability and controlled reactivity under standard conditions.
4-Fluoro-3-methylbenzonitrile serves as a versatile building block in medicinal chemistry, enabling the synthesis of substituted benzimidazoles and other heterocyclic scaffolds. Its trifunctional substitution pattern—fluorine, methyl, and nitrile—offers orthogonal reactivity for late-stage functionalization. The compound exhibits excellent bench stability and compatibility with standard coupling reactions, facilitating efficient purification and integration into multi-step synthetic sequences.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 3439
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H302+H312-H315-H319-H331-H335
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Precautionary Statements : P264-P270-P330-P405-P501
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Lot numbers can be found on the outside label of a product: