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CS-W001157 4
Total: USD 88.00

2,3-Dihydro-1H-cyclopenta[b]quinolin-9-ylamine

  • CAS No. 18528-78-4

  • Cat. No. CS-W002647
  • Purity≥98%
  • MDL No.MFCD00618440
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2,3-Dihydro-1H-cyclopenta[b]quinolin-9-ylamine|CS-W002647

Structure of 18528-78-4

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Description

This bicyclic amine features a fused cyclopentaquinoline scaffold with a primary amine at the 9-position, offering enhanced stability and solubility in organic media. The rigid framework supports efficient integration into bioactive molecules, enabling direct coupling in medicinal chemistry workflows.

Application

2,3-Dihydro-1H-cyclopenta[b]quinolin-9-ylamine serves as a versatile heterocyclic building block for medicinal chemistry and materials science applications. Its fused polycyclic scaffold exhibits enhanced metabolic stability and favorable π-stacking properties. The primary amine functionality enables straightforward derivatization via acylation, alkylation, or reductive amination, facilitating the synthesis of targeted analogs. Bench-stable and compatible with standard coupling protocols, it functions effectively in both solution-phase and solid-phase synthetic workflows.

General Information

  • CAS No. 18528-78-4
  • Cat. No. CS-W002647
  • Purity ≥98%
  • MDL No. MFCD00618440
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₂N₂
  • Molecular Weight 184.24
  • Synonym(s) 9-Amino-2,3-dihydro-1H-cyclopenta[b]quinoline
  • SMILES NC1=C(CCC2)C2=NC3=CC=CC=C13

Computational Chemistry Data

  • TPSA   38.91
  • LogP   2.3057
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

Safety Information

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GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3259
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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