3-(4-Aminophenyl)pyridine

Name: 3-(4-Aminophenyl)pyridine
Brand: ChemScene
Availability: InStock
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CAS No. 82261-42-5
Cat. No. CS-0206624
Purity≥97%
MDL No.MFCD00956763

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Structure of 82261-42-5

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Description

3-(4-Aminophenyl)pyridine features a conjugated system linking an electron-rich aniline moiety to a pyridine ring, enabling strong π-stacking and directional intermolecular interactions. This structural arrangement supports its role in constructing functional materials for organic electronics and pharmaceutical intermediates. The molecule exhibits enhanced solubility in polar solvents and stability under standard bench conditions, facilitating straightforward handling in synthesis workflows.

Application

3-(4-Aminophenyl)pyridine serves as a versatile building block in medicinal chemistry, enabling direct coupling reactions via its pendant aniline and pyridine functionalities. Its stability under standard reaction conditions facilitates incorporation into kinase inhibitors and other bioactive heterocycles. The molecule functions effectively in Suzuki-Miyaura and Buchwald-Hartwig couplings, offering predictable reactivity and straightforward purification.

General Information

CAS No. 82261-42-5
Cat. No. CS-0206624
Purity ≥97%
MDL No. MFCD00956763
Storage RT, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₁H₁₀N₂
Molecular Weight None
Synonym(s) 4-Pyridin-3-ylaniline
SMILES C1=CC(=CN=C1)C2=CC=C(C=C2)N

Computational Chemistry Data

TPSA 38.91
LogP 2.3308
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

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3-(4-Aminophenyl)pyridine

CAS No. 82261-42-5

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